Placental Site Nodule (PSN): An Uncommon Diagnosis with a Common Presentation

Placental site nodule is an uncommon, benign, generally asymptomatic lesion of trophoblastic origin, which may often be detected several months to years after the tenancy from which it resulted. PSN usually presents as menorrhagia, intermenstrual bleeding or an abnormal pap smear. PSN is benign, but it is important to distinguish it from the other benign and malignant lesions like decidua, placental polyp, exaggerated placental site and placental site trophoblastic tumor and squamous cell carcinoma. Follow ups of typical PSNs do not show recurrence or malignant potential.

Gestational and Non-gestational Trophoblastic Disease. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry No. 032/049, December 2015). - Abstract - Europe PMC

Histological image of placental site trophoblastic tumor showing

Placental site nodule - Wikipedia

Placental Site and Epithelioid Trophoblastic Tumours: Rare Varieties of Gestational Trophoblastic Neoplasia

Gestational Trophoblastic Disease

Placental Site Nodule (PSN): An Uncommon Diagnosis with a Common Presentation

Pathology Outlines - Placental site nodule

Pathology Outlines - Placental site nodule

Placental Site Nodule (PSN): An Uncommon Diagnosis with a Common Presentation

Placental site nodule: A tumor like trophoblastic lesion - rare case report